100,000-woman randomized trial offers lessons on judging medical AI by patient outcomes
EricTopol · x · 2026-09-08
Eric Topol highlights Kristina Lång's Nature Medicine piece distilling lessons from one of the first and largest randomized trials of AI in medicine: over 100,000 women undergoing mammography with or without AI-supported interpretation. The core argument: the first generation of medical AI was judged by whether algorithms matched clinicians; the next generation must be judged on whether well-designed human–AI systems actually improve patient outcomes — a shift from algorithmic metrics to real clinical benefit.
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