GPT-6 Astra designs GFP-IL2 fusion protein in 9 minutes, vetted by structural biologist

DeryaTR_ · x · 2026-09-07

Computational biology researcher DeryaTR asked GPT-6 Astra to predict the 3D structures of GFP and interleukin-2 (IL-2), then design a fusion protein combining the two—which doesn't occur naturally—in just 9 minutes. Drawing on years of hands-on work with both proteins, the author attests the result is scientifically correct, down to the precise linker sequence, and believes the construct would likely express and actually work if synthesized.

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