Nobel laureate Capecchi on his workflow, knockout mice, and giving anxiety to pigs
HannesStaerk · x · 2026-09-06
Mario R. Capecchi, who won the 2007 Nobel Prize in Medicine or Physiology for creating the first knockout mice, joins Episode 37 of the Paper Podcast to discuss how he works, how to keep "giving your brain something to do," and his research. Topics include his early work on protein translation of viruses, how knockout mice and gene targeting became the standard for functional genetics and preclinical assessment, and his HOX gene research heading toward inducing anxiety in pigs. 16 minutes.
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