Nature Medicine Proposes Digital Organism: Multiscale Foundation Models to Simulate Life

tomchapin · x · 2026-08-14

A perspective in Nature Medicine envisions the next frontier of AI in biology: a digital organism. Instead of another protein model or virtual cell, it proposes connecting foundation models across DNA, RNA, proteins, cells, tissues, and whole organisms into a multiscale system for predicting, simulating, and eventually programming biology. The authors suggest AlphaFold may have been only the beginning.

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