Running 35B Models on a Single RTX 5080: Migrating from llama.cpp to vLLM

McFlurriez · reddit · 2026-08-11

A developer is seeking advice on migrating their local LLM inference setup from llama.cpp to vLLM. Currently running a Qwen3.6-35B-A3B model on a single RTX 5080 using llama.cpp, they have to offload some layers to the CPU and are limited to a single parallel request (-np 1).

To support subagents in their coding harness, they want to switch to vLLM for better parallel request handling. However, they are finding vLLM's configuration complex and specifically ask how to replicate the -ncmoe 20 setting (for MoE expert offloading) from llama.cpp in vLLM.

Original post →

More from Infra

Infra channel →