Open-Source Model Self-Iteration for Structural Biology

MaziyarPanahi · x · 2026-07-12

The author demonstrates an open-source agentic workflow for structural biology: the model first generates/views results in Mol, then uses Qwen3-VL to self-evaluate the rendering, iterating until the drug's conformation in the pocket is optimized.

He emphasizes that the real breakthrough isn't just "generating an image," but the closed loop itself: 提议 → 观察 → 批判 → 改进. The author suggests that applying this same mechanism to real lab equipment like microscopes could create agents capable of continuous iteration in wet labs. He concludes by asking the community what they want it to research next.

Related event: Open-source AI tackles structural biology via GLM-5.2 and Qwen3-VL self-correcting loop(5 posts)→

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