Two Lines of Prompting Boosts Bio Task Performance
kenbwork · x · 2026-07-11
The author published a new blog post discussing the impact of behavioral prompting on model performance in frontier biological tasks.
The key conclusion is that adding just two lines of behavioral prompts can significantly boost the model's performance on these tasks. The author uses this to explain why the Pi harness outperformed Claude Code and Codex on most benchmarks in their tests (based on results at the time of publication).
The article also introduces their evaluation framework at LatchBio:
- benchmarks.bio: A model benchmark for frontier biological tasks
- Tx-Bench-PP
- ScBench-Long
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