RFD4-Proteina Designs Phosphorylation-Binding Proteins Beyond the 20-Amino-Acid Limit

RFD4-Proteina extends RFdiffusion-based protein design beyond the standard 20 amino acids, now supporting phosphoserine and phosphothreonine binders after phosphotyrosine, including binders that distinguish adjacent phosphorylation sites on histones.

2026-10-21 ~ 2026-10-22 · 2 related posts