Baker Lab Designs Cysteine Proteases from Scratch, Boosting Activity 58-Fold
David Baker's lab de novo designed cysteine proteases, with 13 of 69 designs cleaving substrates. Four 'unlikely' mutations boosted Dokki-15's catalytic efficiency 58-fold.
2026-09-26 ~ 2026-09-26 · 2 related posts
- Baker lab de novo designs cysteine proteases: 13 of 69 designs cleave paired substrates — AllThingsApx · 2026-09-26
- Four 'unlikely' mutations boost designed protease Dokki-15 turnover 58x — AllThingsApx · 2026-09-26