A weekly curve concordance agent to catch inconsistent scientist curve calls

nlarusstone · x · 2026-11-16

Day 28 of the author's "an agent a day" series tackles scientific data hygiene: scientists draw dose-response curve boundaries differently, and across many assays and teams those decisions compound into big consequences for which molecules advance.

The author shares a ready-to-adapt prompt for a weekly Curve Concordance Agent: review raw data, fitted curves, and which points scientists included or excluded; compare decisions across scientists, experiments, and history; flag disagreements that would meaningfully change potency, hit classification, or candidate ranking; propose consistent rules from historical decisions for team review — without auto-changing approved results.

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