Free textbook 'Decoding Genomes' teaches sequence analysis to phylodynamics
burkov · x · 2026-11-15
Tanja Stadler et al. (2024) released a free online textbook, Decoding Genomes: From Sequences to Phylodynamics.
- Builds from evolution and probability foundations toward statistical and computational methods
- Covers sequencing, assembly, alignment, GWAS, models of molecular evolution, and phylogenetic tree reconstruction
- Both conceptual and practical: why sequence analysis matters, how to plan and run it, and how to interpret results
- Infers processes that can't be directly observed from DNA/RNA sequences plus phenotypic data
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