A Weekly "Scientific Skeptic" Agent to Falsify Your Research Assumptions, With Prompt

nlarusstone · x · 2026-11-15

The author proposes using an AI agent as the "perfect research skeptic" — able to process huge amounts of data with no emotional attachment to your current directions, fixing the human tendency to avoid challenging obvious assumptions.

He shares a tweakable prompt template: run the agent weekly over all ongoing team work, identify unsupported assumptions and alternative explanations, and propose experiments designed to falsify them. If hypotheses aren't written down explicitly, the agent first drafts them for review. Part 27 of his "an agent a day keeps Phase 2 failures away" series.

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