Original paper: multi-tissue metabolomic signatures of five longevity interventions
Dr_Singularity · x · 2026-11-14
This is the original Frontiers in Aging paper behind the previous tweet: a University of Michigan-led team performed multi-tissue metabolomic profiling of male UM-HET3 mice under five longevity interventions (rapamycin, acarbose, 17α-estradiol, canagliflozin, caloric restriction), finding convergence on elevated ergothioneine and lipid remodeling, with an AI pipeline distinguishing treated from control mice at high accuracy. Duplicate of the same event; see the earlier item for details.
Related event: Five life-extending interventions share ergothioneine metabolic signature(2 posts)→
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