Nature: enzyme granzyme K drives tissue ageing; knocking it out improves organ function in aged mice
AnnaCiaunica · x · 2026-11-13
Nature reports researchers identified granzyme K, an enzyme that drives ageing in the body's tissues (published in Immunity). Aged mice engineered to lack it showed improved heart and liver function and less kidney damage. Drugs lowering this protein might one day combat ageing without impairing immune defences.
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