Carl Edwards' AssayBench talk: predicting biology and what to measure next

kchonyc · x · 2026-11-13

Carl Edwards shared slides from his AIAS/Chen Institute talk framing AI for biology around the question "can we solve biology?" He defines solving biology as precisely predicting and controlling a biological system's functional behavior — the "virtual cell" paradigm — and argues biology behaves more like language than physics: an evolved system full of exceptions (phages in mucus, ecDNA cancer genes, bacteria synthesizing new genes from noncoding RNA), which is why rule-based systems failed. He presents a lab-in-the-loop workflow — pick the next experiment, measure what cells do, learn from results — via his AssayBench and AssayLoop projects.

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