Drug design as anime: add a square ring, then four fluorines, gasps ensue
gleech · x · 2026-11-13
A chemistry meme dramatizes medicinal chemists' obsession with fluorines and square rings: to make a 'too normal' molecule publishable, someone suggests adding a cyclobutane, then a lone-wolf chemist heroically adds four fluorines. The punchline image is the real structure of N-Desmethylapalutamide, which contains both.
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