ProTEUS: a mutation-resolved world model for closed-loop protein evolution, SOTA on protein engineering

LeoTZ03 · x · 2026-11-12

ProTEUS tackles a holy grail of molecular engineering: efficiently finding mutations that push a protein toward a desired property among 20^L possibilities. It is a mutation-resolved world model for closed-loop protein evolution, achieving SOTA on various protein engineering tasks and opening a new axis of scaling.

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