AlphaGenome 2 now available via API for non-commercial research
sundarpichai · x · 2026-11-12
DeepMind released AlphaGenome 2, available today through the AlphaGenome API for non-commercial research.
- The model predicts how DNA sequence variants affect hundreds of human cell types and states, bridging single-cell biology and human genetics
- It redesigns the architecture to zoom from broad-tissue averages to individual cell types, catching disease-relevant variant effects broad-tissue models miss
- Builds on AlphaGenome 1 and the AlphaGenome Atlas, which covered all 9 billion possible single-letter changes in the human genome
- Paper and API are public, targeting rare disease, complex traits, and fundamental biology research
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