1961 mouse embryo fusion experiment revealed remarkable regulative capacity

AnnaCiaunica · x · 2026-11-11

A reposted embryology history thread: in 1961, Tarkowski removed the zona pellucida from two 8-cell mouse embryos, causing them to adhere and fuse. The fused embryos implanted in foster mothers and developed into normal mice, revealing mammals' extraordinary regulative capacity — even after doubling their starting cell number, embryos adjust growth to produce normal-sized animals. Part of a stem-cell research history series (42/175) from the boroviak lab.

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