ProTEUS: a mutation-resolved world model for closed-loop protein evolution
Yikun Zhang · hf · 2026-11-11
ProTEUS is a mutation-resolved world model for protein evolution from Foundry Bioscience, MIT, and Stanford teams. It combines sequence, evolutionary, and structural representations with fast all-atom prediction and closed-loop feedback to guide protein evolution and improve mutant activity — using the world model to predict mutation effects and iteratively optimize protein function in a closed loop.
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