Rare-disease eval nears saturation: Gemini 4 Carbon and Claude Fable 5.2 both hit 61.5%

danielmckinn0n · x · 2026-11-11

RareBench creator danielmckinn0n shares the latest results: on the rare-disease diagnosis benchmark, Google DeepMind's Gemini 4 Carbon and Anthropic's Claude Fable 5.2 tie for first at 61.5% (75/122 cases) — versus just 9% for GPT 5.4 when the project started. With the task near saturation, a harder RareBench v2 is in the works. On LabBench, which tests interpreting real rare-disease lab data and predicting the next experiment, Gemini Carbon leads alone at 50.3%. The author argues AI is on a trajectory to help solve rare disease within a few years.

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