Geodesic launches NovaAtom-Lite, beating AlphaFold 3 on antibody-antigen structure prediction
QuanquanGu · x · 2026-11-11
Geodesic introduced NovaAtom-Lite, an all-atom structure prediction model for drug discovery that predicts structures of proteins, nucleic acids, and their bound molecules, including how they fit together.
On FoldBench antibody–antigen structure prediction (DockQ ≥ 0.23): NovaAtom-Lite scores 79.07% (n=172), vs 75.58% for IsoDDE and 47.90% for AlphaFold 3 (n=167). Evaluation uses 5 seeds × 5 samples with top-1 selected by the model's own ranking score. Available now via Geodesic API and NovaDDE.
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