5-month-old, 15-person Geodesic launches NovaAtom-Lite, beating Isomorphic's IsoDDE and AlphaFold 3 on FoldBench
QuanquanGu · x · 2026-11-11
Geodesic Intelligence introduced NovaAtom-Lite, an all-atom structure prediction model for drug discovery that predicts proteins, nucleic acids, and bound molecules.
- Scores 79.07% on FoldBench antibody–antigen prediction (DockQ ≥ 0.23, n=172), beating Isomorphic Labs' IsoDDE (75.58%) and AlphaFold 3 (47.90%, n=167)
- Ranks No.1 on FoldBench protein–ligand at 77.06%
- Evaluation uses 5 seeds × 5 samples with top-1 selected by the model's own ranking score
The company is only five months old with 15 people; the model is live via the Geodesic API and NovaDDE.
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