Geodesic launches NovaAtom-Lite, beating AlphaFold 3 on antibody-antigen prediction

QuanquanGu · x · 2026-11-11

Geodesic launched NovaAtom-Lite, an all-atom structure prediction model for drug discovery covering proteins, nucleic acids and their binders. On FoldBench antibody–antigen prediction (DockQ ≥ 0.23) it scores 79.07% (n=172) vs IsoDDE's 75.58% and AlphaFold 3's 47.90% (n=167), using 5 seeds × 5 samples with model-ranked top-1. Live via Geodesic API and NovaDDE.

Related event: Geodesic Releases NovaAtom-Lite, Beating AlphaFold 3 on Antibody-Antigen Benchmark(7 posts)→

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