EMBO paper torches aging research dogma: biological age, epigenetic clocks all questioned
MaxUnfried · x · 2026-11-10
Gerontologist Richard A. Miller publishes an open-access EMBO Journal commentary, 'Seven ways not to think carefully about aging,' systematically criticizing common conceptual schemas in biogerontology: a single cause of aging, personal 'biological age,' published clocks measuring it, cellular age, cellular rejuvenation, biomarkers as aging-rate measures, healthspan-vs-lifespan tradeoffs, and the Hallmarks of Aging framework. Retweeter MaxUnfried, a reviewer of the paper, adds that mouse studies mostly serve academic publishing rather than human aging science, while noting accumulated mouse data may still point to new anti-aging interventions.
More from Research
- Preprint: Learning Tool-Output Projections from Agent Traces Cuts Billed Tokens up to 56% — solyarisoftware · 2026-11-10
- Shanghai AI Lab's Sage-Taiyi tops AI co-scientist benchmark, lifts reaction yields to 84% — Shanghai-AI-Laboratory · 2026-11-10
- SIRIS benchmark: LLMs can't reliably tell when simulator errors invalidate design recommendations — MicrosoftResearch · 2026-11-10
- How many exposures does a world model need? WARC learns unseen game mechanics in ~80 exposures — third-intelligence · 2026-11-10
- Tencent Hunyuan's FewStepRL adapts RL fine-tuning to few-step diffusion models — Tencent-Hunyuan · 2026-11-10
- BioEmu2 simulations show ligand-triggered conformational shifts in maltose binding protein — FrankNoeBerlin · 2026-11-10