External chemists rate Claude's synthesis routes at early-graduate-student level

claudeai · x · 2026-11-10

Anthropic discloses that external collaborators rated Claude's synthesis route work at the level of an early graduate student; the routes haven't been lab-tested yet. The four molecules came from unpublished syntheses in the labs of Noah Burns (Stanford), Timothy Newhouse (Yale), and Sarah Reisman (Caltech). The model self-checked its plans by writing and running code to confirm, atom by atom, that each compound followed from starting materials, replaced reactions that could damage the molecule, and flagged steps most likely to fail.

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