RFdiffusion protein binders: 158 of 188 designed binders bind TrkA below 1 µM
HannesStaerk · x · 2026-11-07
A reading group session revealed wet-lab results for RFdiffusion 4 (RFD4-Proteina) protein design: 158 of 188 designed binders bound TrkA below 1 µM, versus only 18 of 60 for the next-best method — a dramatic success-rate gap. Nate Corley and Kieran presented the results on Zoom.
Related event: Baker Lab and NVIDIA Release RFD4-Proteina with 84% Binder Success Rate(5 posts)→
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