NEJM AI randomized trial: predictive algorithm catches autoimmune diseases years earlier
EricTopol · x · 2026-11-06
Eric Topol highlights a randomized assessment in NEJM AI showing a predictive algorithm can avoid the years-long diagnostic delays typical of autoimmune diseases.
The Kaplan-Meier figure shows that within 800 days of a positive ANA test, cumulative diagnoses reached 7.9% (79/954) in the intervention arm vs 4.6% (46/1006) in control, P<0.001 — algorithm-flagged patients were diagnosed substantially earlier, demonstrating real clinical value.
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