Nature Communications study pinpoints high-level visual cortex as site of one-shot learning
MacrinePhD · x · 2026-11-05
New research by Hachisuka, Shor, and Biyu J. He in Nature Communications reveals the neural and computational mechanisms behind one-shot perceptual learning in humans.
Combining 7T fMRI, intracranial recordings, and deep neural network modeling with top-down feedback, the study identifies the high-level visual cortex as the key site of learning-induced plasticity, showing how a single visual experience can permanently transform perception. A companion paper from the same lab earlier this year showed one-shot learning-induced activity changes onset in IT before early visual cortex, with plasticity likely residing in IT and an ANN model capturing the phenomenon.
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