Deep Principle open-sources Hydrogen-1.0, a GLM-5.3-based model for chemistry research
truecakesnake · reddit · 2026-11-03
Deep Principle released Hydrogen-1.0, an open-weight model post-trained from GLM-5.3 for chemistry, materials science, and life sciences, powering their Mira AI Scientist.
- The model targets a real lab pain point: reconstructing context scattered across results, notes, and decisions to answer questions like "what did yesterday's experiment show" or "what should we try next."
- A short film demonstrates the intended workflow — reviewing evidence, exploring reaction pathways, logging bench work — with the researcher making all decisions.
- Weights are on Hugging Face, with a technical write-up covering evaluations and model-plus-tool examples.
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