H200 loses money even fully busy: GPU choice beats inference engine for hosting economics

teortaxesTex · x · 2026-11-03

Yingjun Wu's analysis of hosting DeepSeek V4.1 Flash shows GPU choice matters far more than the inference engine: H200 (8 GPUs) earns only $1.6 per GPU-hour at full load and needs 244% utilization to break even — unprofitable at any utilization. B300 (8 GPUs) earns $21.4 and breaks even at 35% utilization (31%/51% gross margin at 50%/70% busy). GB300 NVL72 ranges from $18.1 full-load revenue (84% break-even) standard, to $32.0 with NVIDIA Dynamo (48% break-even), to $64.7 with rack-tuned vLLM (24% break-even, 66% margin at 70% busy). teortaxesTex adds: to profit on Hopper you must own compute — rental margins price out resellers.

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