Profluent Bio applies language models to design gene editors, says Nathan Benaich

nathanbenaich · x · 2026-11-03

At Nathan Benaich's MTS Live conversation on the State of AI Report 2026, he explained that protein sequences can be written as strings of letters, and language models can learn to design them. Air Street Capital portfolio company Profluent Bio is applying this approach to gene editors.

It's a representative AI-for-Science case in biotech: treating protein engineering as a language generation problem to create novel sequences, rather than merely screening natural ones. The full discussion is available via the stateof.ai report.

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