'Biology is just a data problem?' One mitochondrial peptide shows why that's naive

iScienceLuvr · x · 2026-10-30

Quoting a viral rant against the 'collect enough omics, simulate the whole cell' take: the humanin peptide encoded inside mitochondrial 16S rRNA is a ribosome structural part, translates to 24 aa in the cytosol but 21 aa in mitochondria due to a different genetic code, with nobody sure which occurs — plus 13 nuclear copies, secretion into blood, a receptor that's literally a mitochondria detector, and Bax binding to block apoptosis. iScienceLuvr's takeaway: biology is messy and rule-free, which is exactly why it's so hard to 'solve'.

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