Single-nucleus RNA-seq atlas reveals distinct features of early-onset colorectal cancer in the young

EricTopol · x · 2026-10-29

Eric Topol highlights a new Nature Medicine study: researchers built a single-nucleus RNA-seq atlas of colorectal cancer across the age continuum, revealing distinct molecular features of early-onset colon cancer at single-nucleus resolution. The findings include both unfavorable traits and potentially helpful clues for understanding why this cancer is rising in young people, offering a reference dataset for mechanism and prevention research.

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