Divergence Labs and Anthropic use Claude to discover antibody therapy for food allergy
anshulkundaje · x · 2026-10-28
Divergence Labs, in collaboration with Anthropic, reports rapid initial progress toward an antibody treatment for food allergy, discovered with Claude's help. The condition affects over 200 million people worldwide.
Key mechanism: Xolair, the only approved antibody for food allergy, sequesters circulating IgE—but mast cells stay sensitized for weeks to months because IgE dissociates extraordinarily slowly from its receptor FcεRI. The team envisions a treatment that actively pulls IgE off FcεRI rather than waiting for natural dissociation, arguing AI can unlock next-generation antibody therapeutics with more effective mechanisms.
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