Karpathy open-sources AutoResearch: AI agents that run the full research loop autonomously

mdancho84 · x · 2026-10-22

Andrej Karpathy has open-sourced AutoResearch, a system of AI agents that autonomously run the research loop — not just answering questions but proposing, executing and iterating on experiments.

A progress chart shows 83 experiments with 15 kept improvements, driving validation Brier scores from 0.998 down to 0.977, with auto-generated rationales for each accepted change (model swaps, sampling-frequency tweaks, prompt edits).

The README opens with a tongue-in-cheek note from 'Karpathy, March 2026': frontier research once done by 'meat computers' between group meetings is now the domain of autonomous agent swarms on compute clusters, with self-modifying code beyond human comprehension.

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