Baker Lab and NVIDIA open-source RFD4-Proteina for generative protein design

AllThingsApx · x · 2026-10-21

RFD4-Proteina is now open-source (BSD-3-Clause) on GitHub, already at 103 stars. The flow-matching foundation model for generative protein design with rich conditioning comes from Baker Lab × NVIDIA GenAIR.

No install needed: design runs in-browser via Hugging Face Studio Spaces. The repo includes quick start, workflows, tutorials, and Docker setup; project page at rfd4-proteina.org with an accompanying paper.

Related event: NVIDIA and Baker Lab Open-Source RFD4-Proteina Protein Design Model(35 posts)→

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