Omnii-1 genome model debuts: first AI-designed phages ever given to a human patient

JosephJacks_ · x · 2026-10-21

Michael Poli and team launched Omnii-1, a next-generation multimodal genome language model billed as a major step toward general biological intelligence. In a world first, Omnii-1 designed the first AI-generated bacteriophages to be administered to a human patient with an antibiotic-resistant infection under compassionate use. The model builds on a long line of genome LM research—new architectures, multimodal pretraining, and mid/post-training methods tailored to biological data—and ships with 8 full-length technical blogs.

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