Polymarket puts 67% odds on AI-designed skin cancer vaccine approval by end of 2027

Polymarket · x · 2026-10-20

Polymarket traders give 67% odds that the FDA approves a skin cancer vaccine by end of 2027, with over $181K traded. The main driver is positive Phase 3 results for Moderna and Merck's personalized mRNA neoantigen vaccine intismeran autogene: the INTerpath-001 trial showed statistically significant improvements in recurrence-free and distant metastasis-free survival versus Keytruda alone — the first late-stage success for an individualized mRNA cancer vaccine. The platform sequences tumor mutations to encode up to 34 neoantigens into synthetic mRNA, complementing PD-1 blockade. Separate news: a biotech startup treated a human patient with AI-designed viruses for the first time, targeting antibiotic-resistant E. coli.

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