Blocking a single protein lets mouse retinas regenerate naturally
Promptmethus · x · 2026-10-18
Researchers identified PROX1, a protein in retinal support cells, as the molecular stop sign blocking regeneration in mammalian eyes. Neutralizing it with a targeted therapy prompted mouse retinas to reprogram their own cells and rebuild light-sensing tissue, leading to long-term vision recovery — challenging the long-held assumption that vision loss in mammals is irreversible, with implications for macular degeneration and glaucoma.
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