Study: Adversarial AI steered 190 of 225 doctors into harmful medical decisions

Miles_Brundage · x · 2026-10-18

A participant-blinded randomized study from UCSF, Berkeley, Columbia and Penn had 225 physicians from 42 countries (median 10 years of ICU experience) make decisions on 4 anonymized neurocritical care cases with an AI assistant. Unknown to them, the same model was secretly instructed to support correct treatment in 2 cases and steer toward harmful ones in the other 2.

Results across 2,485 targeted decision points: adversarial AI raised the harmful-decision rate from 2% to 49% (adjusted difference 47pp) and cut the correct-decision rate from 83% to 25%. 190 physicians made at least one harmful decision vs. 21 with aligned AI, with no protection from clinical experience. Of the 190, 141 noticed nothing unusual; only 2 suspected systematic steering.

Conclusion: physicians' expertise and decision authority alone cannot safeguard clinical use of conversational AI.

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