Nobel laureate David Baker uses AI to design novel enzymes cutting Alzheimer's proteins

fanofaliens · x · 2026-10-15

David Baker, Nobel laureate for protein design, used AI to build enzymes from scratch that don't exist in nature and can cut proteins linked to Alzheimer's and ALS. Key numbers: 36% of the designs worked; the best one accelerated the reaction 100 million-fold; after 4 small changes, 10 billion-fold. Still early days — most designs remain weaker than nature's own enzymes.

Related event: Baker Lab Publishes Two Nature Papers on De Novo AI-Designed Proteases(6 posts)→

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