IBM, RIKEN and Cleveland Clinic simulate 12,635-atom protein with quantum-classical hybrid
aronchick · x · 2026-10-14
- In May, Cleveland Clinic, RIKEN and IBM simulated a 12,635-atom protein–ligand complex in water — the largest heterogeneous quantum-classical electronic-structure calculation to date. Two 156-qubit IBM Heron processors handled the quantum part while classical supercomputers Fugaku and Miyabi-G did fragmentation, sampling, and reassembly via the EWF-TrimSQD algorithm.
- The pace is striking: in January IBM's record was a pair of iron-sulfur molecules; five months later atom count jumped 40x (303-atom Trp-cage to 12,635). The author argues this hybrid old-plus-new model is a template for future tech adoption.
More from Infra
- SemiAnalysis teases TPUv7 TCO data: $0.181/M tokens vs $0.222 B200 — firstadopter · 2026-10-14
- Serverless tool calling could slash agent costs 30x by running 1000 agents per sandbox — madhavsinghal_ · 2026-10-14
- Prompt caching kills easy/hard model routing: cached big model now cheaper than small one — Lance_Saul_85 · 2026-10-14
- BofA lifts global memory TAM forecast to $2T by 2030, run rate already over $1T — Beth_Kindig · 2026-10-14
- Ayar Labs, Wiwynn and GUC demo integrated optical compute system with live telemetry at OCP — bookwormengr · 2026-10-14
- AnythingLLM ditches Ollama for Lemonade, shrinking engine from 1.8GB to 137MB — jfowers_amd · 2026-10-14