Greg: AI can't generate human observations that haven't happened — that's the rate limiter
gregmushen · x · 2026-10-12
Responding to AI-longevity optimism, gregmushen argues people like Sinclair have made the same claims for decades but hit the same wall: once you have a hypothesis, you must progressively test it in human subjects — there is no workaround. AI helps form better hypotheses and design experiments, but it cannot generate observations that need to happen in living humans over years, which is the rate-limiting factor. No evidentiary basis exists for escape velocity within a few years, he says.
Related event: Debate Rages Over Whether AI Can Accelerate Longevity Research(4 posts)→
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