194-year-old tortoise's clean mitochondrial gene switches spark AI longevity debate

reallyoptimized · x · 2026-10-12

Citing a Vanderbilt University Medical Center report on Jonathan, a 194-year-old giant tortoise, the author notes its mitochondrial gene switches stayed orderly for two centuries, with 272 promoters kept clean, mostly around mitochondria and DNA repair. He argues the longevity blueprint already exists and AI will turn blueprints into biology 'exponentially,' predicting humans will live for centuries — kicking off a debate with gregmushen on whether AI can actually speed up longevity research.

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