Local DeepSeek on GPU+CPU+NVMe: 21x prefill speedup and 95% TTFT reduction after weeks of tuning

HankYeomans · x · 2026-10-12

A developer shares full stats from day one to today for their hybrid GPU+CPU+NVMe local deployment of DeepSeek (v4.1 MXFP4 quantization), after exhausting patches and tweaks:

Key takeaway: with sustained tuning, the prefill bottleneck of CPU-offload + NVMe tiering can be dramatically mitigated, cutting long-context time-to-first-token from over two minutes to seconds — compelling real-world data for running large models locally on consumer hardware.

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