Optimized one_hot_encode finishes all 455 hg38 contigs in 1.5s — and the ethics of speeding up others' code
jmschreiber91 · x · 2026-10-11
Developer jmschreiber91 shares progress on optimizing code in an open-source bioinformatics project: the latest round pushed onehotencode to encode all 455 contigs of hg38 in 1.5 seconds, now merged. Combined with agentic skills, the whole workflow runs much faster than before.
He also raises the collaboration-ethics question in this workflow: taking someone else's code, speeding it up, and releasing it as your own is unacceptable and should be shunned — meaning there are clear norms around "speeding up others' code."
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