tangermeme, a toolkit for interpreting cis-regulatory logic, published in Nature Methods

jmschreiber91 · x · 2026-10-09

Jacob Schreiber's tangermeme toolkit is now published in Nature Methods as an open-access brief communication.

It implements the primitives of genomic sequence-to-function modeling with efficient, tested, composable functions — positioned as "everything-but-the-model" for genomic deep learning, distilling learned cis-regulatory patterns into human-interpretable insights after a model proves its predictive performance.

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