Models are reasoning tech; biology lacks the verification loops that math and coding have

holdenmatt · x · 2026-10-08

Responding to the view that models aren't good at biology yet, Holden Karnofsky offers a framing: models are "reasoning technology," but they need complementary "verification technology" to work well. Math has Lean; coding has compilers, linters, tests and CI. Biology lacks cheap, fast verification loops. He asks whether biology can develop better verification loops, or whether they are long and expensive for intrinsic reasons.

Related event: AI Still Falls Short in Biology, and Verification Tech May Be the Missing Piece(3 posts)→

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