First-of-Kind RCT: GPT-4o Respiratory Chatbot Beats Web Search for Layperson Diagnosis

EricTopol · x · 2026-10-05

A nationwide randomized trial in Nature Health compared LungDiag, a task-constrained WeChat chatbot built on GPT-4o with a respiratory knowledge layer, against standard mobile web search for layperson respiratory diagnosis and triage — among the first prospective RCTs of public-facing medical chatbots, showing improved diagnostic accuracy.

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